

Oh boy it’s my time to shine!
I’m working in aging right now. Heard of Dr. David Sinclair since he was the corresponding author on a paper I was curious about… So this is what his lab is doing.
Two important disclaimers:
- Success in cellular research rarely translates to something viable in the clinic. A lot of chemicals don’t behave the same way in cells as in actual animals or humans. Heck, a good number of phase 2 drugs even fail, and these haven’t even made it into phase 1… so I wouldn’t be too optimistic about them.
- The journal Aging is not the most prestigious journal especially for someone working at Harvard Medical School (HMS) to be honest. I’d be more excited if this was published in Nature Aging or Nature Communications or something. If this ever gets published in New England Journal of Medicine (a very prestigious journal only for clinical studies) then we have some news.
The link between cell senescence and aging is something actively being studied tho.
And, if anyone is curious about this topic: I’m also very actively following Dr. Vadim Gladyshev who is also from HMS and is working in aging, I believe he is doing some wet lab-biology on a similar area as well. Feels like his research is sometimes a bit ahead of his time but I think his work has great potential.













Second this. Also link to relevant Cory Doctorow article for those interested: https://pluralistic.net/2023/05/17/free-as-in-freefile/
Personally, last year my taxes were somewhat complex, but I filed my taxes using the fillable electronic forms alone anyways; IRS actually nicely corrected mistakes I made on the tax form and sent me back a check… For most ppl you can probably just go to a random free provider as suggested by the IRS.
No need to use TurboTax for anything unless tax situation is super complex & you can’t/don’t want to read the IRS instructions